US12571732USUSPTO Grant XML

Methods and systems for point-of-care coagulation assays by optical detection

An assay system includes an excitation light source to output excitation light having a first wavelength; an optical reference positioned to absorb the excitation light from the excitation light source and to output an optical signal based on the excitation light, where the optical signal has a second wavelength that is different from the first wavelength; a reaction chamber containing a reactant and an inlet to receive a test sample to produce a fluid that is based on the test sample and the reactant, where the reaction chamber is positioned to receive the optical signal from the optical reference; and an optical receiver positioned to detect an amount of the optical signal that passed through the reaction chamber containing the fluid.

Patent

Brief

Patent brief

Problem

How can microplastics and similar contaminants be removed from wastewater?

Novelty

Coagulation and flocculation is reinforced by front-page matches on coagulation.

Uses

Water clarification, Wastewater cleanup, Process treatment

Assignee

Instrumentation Laboratory Company

Published

Mar 10, 2026

Inventors

Josef Kerimo, Hansong Zeng, Ron Scharlack, Gert Blankenstein

Domain

Environmental systems

Plain-English summary

Problem

How can microplastics and similar contaminants be removed from wastewater?

Solution

assay system includes an excitation light source to output excitation light having a first wavelength; an optical reference positioned to absorb the excitation light from the excitation light source and to output an optical signal based on the excitation light, where the optical signal has a second wavelength that is different from the first wavelength; a reaction chamber containing a reactant and an inlet to receive a test sample to produce a fluid that is based on the test sample and the reactant, where the reaction chamber is positioned to receive the optical signal from the optical reference; and an optical receiver positioned to detect an amount of the optical signal that passed through the reaction chamber containing the fluid.

Key novelty

Coagulation and flocculation is reinforced by front-page matches on coagulation.

Applications

Water clarificationWastewater cleanupProcess treatment

Relevant search intents

coagulation

Claims preview

1 . An assay system comprising: an excitation light source to output excitation light having a first wavelength; an optical reference positioned to absorb the excitation light from the excitation light source and to output an optical signal based on the excitation light, the optical signal having a second wavelength that is different from the first wavelength; a reaction chamber comprising a reactant and an inlet to receive a test sample to produce a fluid that is based on the test sample and the reactant, the reaction chamber being positioned to receive the optical signal from the optical reference; an optical receiver positioned to detect an amount of the optical signal that passed through the reaction chamber containing the fluid; wherein the optical reference is positioned between the excitation light source and the reaction chamber, and wherein the reaction chamber is positioned between the optical reference and the optical receiver; and a test instrument to detect an analyte or coagulation associated with the test sample based on the amount of the optical signal that passed through the reaction chamber containing the fluid. 2 . The assay system of claim 1 , wherein the reaction chamber holds the test sample in the absence of a colorimetric reagent. 3 . The assay system of claim 1 , wherein the first wavelength ranges from 20 nm (nanometers) to 5000 nm.

Linked approaches

Coagulation and flocculation

Chemical treatment methods that aggregate plastics for removal.

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